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Unraveling the underlying genetics with powerful tools

Variants Deciphered ®

Genomatics is a bioinformatics products company formed to build innovative & inquisitive bioinformatics products.

Proliferation of Genomic Sequencing data due to advances in Sequencing Technologies has created a ‘Genomic Big Data World’. Deciphering the genetic codes in the human genome sequence helps in understanding how genes work together and how they contribute to various aspects like development, function and structure of the human body. That means genes are the fundamental building blocks for the proper and normal functioning of human cell. And abnormalities begin to occur when the gene sequence changes and contributes to diseases! Hence identifying genes and gene variants has become the most important focal point in medical and genomics research.

The Human Genome Sequencing Effort combined with exponential increase in Computational Power has brought in a phenomenal transformational shift in the approaches to well-being of human population/s. World-wide human genome sequencing projects has helped in understanding the structural and functional components of the human genome. Huge expansion in Genetics research has opened up health markets in personalized or precision medicine. We are seeing a proliferation of private firms taking a personalized patient-centric approach with targeted clinical programs, biobanking technologies etc., For such programs to succeed and produce reliable reports or prepare customized treatment plans, high-quality supporting data is utmost necessary.

Powerful and cost-effective diagnostic and predictive computational tools are needed to skim through the outputs of genomic research published. Variants extraction from the biomedical literature by manual curation requires a lot of patience, stringent quality control procedures and agility. These databases contain large structural variants like CNVs (copy number variants), to small-scale variants like SNPs (single-nucleotide polymorphisms), to indels (intragenic insertions and deletions). 

Strong molecular knowledge and computational skills are required to build value based content databases. A secure, flexible, powerful cloud computing environment is needed for accessing these large content databases easily from anywhere in the world.

Genomatics was founded exactly for that ! To build  such great products in the most happening Genomics domain !

Genomatics has envisioned itself to play an important role in producing comprehensive set of products which will enable researchers to analyze their sequence data and find the gene or variant composition and relate it to diseases and drugs.

Genomatics understands unique client requirements and can deliver robust products catering to different needs of clients in the domain. VarDiG-DB is a finely curated database produced by a set of well-trained, highly qualified human curators. The back-end software pipelines and machine learning tools built by Genomatics helps the human curators to produce a refined Variants Database. Carefully selected publications and stringent quality control procedures employed guarantee a reliable set of variants with high ‘Specificity’. And we are quite excited at this point of time, as Genomatics has produced the world’s highest number of manually curated variants!

Genomatics has also produced a SaaS (Software as a Service) product which will help clients to access the variants database using a very user-friendly web interface. The search engine and other built-in tools help in unravelling the underlying variants and decipher the gene, disease, drug associations.

Genomatics with its regularly updated, manually curated databases will play a pivotal role in accelerating scientific research, discoveries and contribute to advancements in human health.